A synthesis of 2-endo-amino-2-exo-hydroxymethylnorbornenes having inhibitory activity against protein kinase C.
نویسندگان
چکیده
منابع مشابه
2-exo,5-endo,8,8,10-Pentachlorobornane
The title compound, C(10)H(13)Cl(5), is a polychlorinated monoterpene and a Toxaphene congener. This compound is also the only penta-chlorinated derivative of camphene formed via ionic chlorination. Previously, the title compound was thought to be 2-exo,5-endo,9,9,10-penta-chloro-bornane, but X-ray structural analysis showed it to have a different structure and rather to be 2-exo,5-endo,8,8,10-...
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A assistência da deslocalização de elétrons sigma ou assistência anquimérica dos elétrons sigma explica grandes diferenças de velocidade na solvólise de 2-exoe 2-endo-norbornilp-bromobenzenosulfonatos. Este estudo foi anteriormente analisado pela teoria dos orbitais moleculares em fase gás. Ao revisitar este antigo problema a partir da teoria quântica de átomos em moléculas (QTAIM), novas infor...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1991
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.39.527